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HERBS FG MATRIX FOR ADVANCE WOUND CARE THERAPY FOR DIABETIC, VENOUS, ARTELOUS ULCER
Author(s) -
Izunobi Felicia Ukamaka,
Einstein George P
Publication year - 2016
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.30.1_supplement.688.14
Subject(s) - medicine , diabetes mellitus , amputation , wound healing , diabetic foot , diabetic ulcers , diabetic foot ulcer , population , surgery , insulin , wound care , endocrinology , environmental health
Over 6 million people in the United States is affected with chronic ulcer. The incidence is expected to as the population ages and as the number of individual with diabetes increase and approximately 15 to 25 % of diabetic patient will develop ulcers. The treatment of uleritic wounds has become a very challenging, most leading to amputation or death. The four cardinal signs of inflammation are (1) Rubor (redness),(2) Swelling, (3) Lost of function leading to acute or chronic ulcer. Most diabetic ulcers and bed sores heal by secondary intention – Here the wounds are chronic and as such there has been loss of tissues of the affected site and enlargement sideways and depth created by the loss of those tissues –including skins subcutaneous tissues and muscles or other fleshly tissues. Beta cells in the islet of Langerhans in the pancreas produces insulin which is responsible for the conversion of glucose into its usable and storage forms. In absence of insulin glucose or sugar will be there by presence and not there by function. The glucose by its physical presence and by lack of the chemical role of energy provision cause these ulcers. Managing the diabetes effectively also contributes a lot in the healing of the diabetic wound and ulcers. Conclusion The Matrix by its presence soak away the glucose in the wounded tissues and the vessels around the wound, thereby enhancing wound healing. In other words it is like a cleanser to the wound which filters out the glucose that is hindering the healing of these wounds. There is a restoration of extracellular membrane which was damaged by nonenzymatic glycosylation, affecting both its structure and function. The inflammation which is response to the infection modified by changes in both chemotaxis and phagocytic function of the white blood cells is healed by application of the Matrix formula. Whether the cleansing or filtration process also extends to the bacteria's which complicates the wound healing is something to be looked into. Support or Funding Information Einstein Medical Institute Corp. USA