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Comparison of Two Administration Forms of a Highly Viscous Fibre Blend on Appetite and Glycemic Response in Healthy Individuals
Author(s) -
AuYeung Fei,
Jovanovski Elena,
Ho Hoang,
Zurbau Andreea,
Jenkins Alexandra L,
Vuksan Vladimir
Publication year - 2016
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.30.1_supplement.405.4
Subject(s) - glycemic , appetite , food science , dietary fibre , glycemic index , chemistry , medicine , zoology , endocrinology , insulin , biology
Objective The effect of viscous fibres on appetite and food intake have been equivocal, limited by the capacity of gel‐formation within the gastrointestinal tract. Differences in fibre administration form many determine the physiological effects of viscous fibres. Using a highly viscous fibre blend (VFB) of two complimentary fibres, konjac glucomannan and xanthan gum, we investigated the acute effects of pre‐hydrating VFB into a solid gel compared to the powdered form on appetite and glycemic response. Methods Eighteen (18) healthy participants completed the study (F: 11/M: 7; Age: 28.6 ± 3.2 years; BMI: 23.3 ± 0.7 kg/m 2 ) and 15 provided blood samples. In an acute, randomized, double‐blinded, cross‐over design, participants consumed 1 of 5 test meals on 5 separate occasions with > 2 day washout period. The test meals were: 50 g available carbohydrates in bread with 5 g VFB as a powder (50Pow), 5 g VFB as a pre‐hydrated gel (50Gel), or a fibre‐free control (50Con), and 25 g available carbohydrates in bread with 25 g available carbohydrates in the gel dessert with 5 g VFB pre‐hydrated into the gel (25Gel) or a fibre‐free control (25Con). All meals consisted of bread, margarine, and a gel dessert which totaled 50 g of available carbohydrates. A metabolically controlled lunch was consumed 180 min later. Satiety was recorded using visual analogue scales. Results The incremental area under the curve (iAUC) after 120 min for blood glucose was lower after 50Pow (mean difference: −40 %, p < 0.001) and 50Gel (mean difference: −23 %, p = 0.049) vs. 50Con. No differences were observed between 50Pow and 50Gel (p = 0.16). Additionally, 50Gel increased satiety after 120 min vs. 50Pow (MD: +26 %, p=0.035) and 50Con (mean difference: +28 %, p = 0.025). The iAUC after 120 min for blood glucose was lower in 25Gel vs. 25Con (mean difference: −28 %, p = 0.006), but no significant differences were observed in satiety. Conclusions These findings suggest that VFB may improve the postprandial glycemic response irrespective of administration mode, but consumption in a pre‐hydrated gel may confer additional benefits from improved satiety. Clinicaltrials.gov Identifier: NCT01657058