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Inulin Effect on Weight Loss and Associated Parameters with The Development of Cardiovascular Disease in Obese Adults
Author(s) -
CastroSanchez Francisco Humberto,
OchoaAcosta Dora Alicia,
ValenzuelaRubio Nancy Guadalupe,
DominguezRodriguez Maribel,
FierrosValdez Jesus Antonio,
VergaraJimenez Marcela
Publication year - 2016
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.30.1_supplement.1176.22
Subject(s) - inulin , weight loss , medicine , waist , obesity , placebo , cholesterol , anthropometry , crossover study , lipid profile , endocrinology , physiology , food science , biology , alternative medicine , pathology
Obesity is one of the most concerning public health problems in Mexico and it has being associated with the development of cardiovascular diseases (CVD). A healthy diet has demonstrated to improve weight loss and blood lipids but also the inclusion of functional foods could be used. Inulin, a non‐digestible carbohydrate, has been shown to have the ability to promote weight loss and improve the lipid profile associated with CVD. The aim of the present study was to examine the effect of addition of inulin plus a moderate carbohydrate diet on weight loss and parameters associated with cardiovascular disease. Sixteen obese dislipidemic subjects were recluted and distributed in a double‐blind, crossover trial for 18 weeks with two eight‐week treatment periods (9g of inulin/day or 9g of dextrose/day as placebo), separated by a two‐week washout period. Anthropometric and lipid profile were recollected at the beginning and the end of each treatment. Both treatments significantly improve weight loss and others anthropometric parameters (BMI, Body fat and also waist and hip circumferences) without statistical difference between them. Inulin significantly increased HDL cholesterol (p<0.05) and tend to reduce triglycerides. Non‐significant changes were observed on Total and LDL cholesterol. In conclusion, we can suggest that the addition to inulin and a moderate carbohydrate diet tend to reduce cardiovascular risk by increasing HDL cholesterol and reduction of triglycerides concentrations.