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Spontaneously Hypertensive Rats Display Exaggerated Increase in Brain Temperature During Acute Physical Exercise in Temperate and Warm Environments
Author(s) -
Drummond Lucas,
Wanner Samuel,
Kunstetter Ana,
Vaz Filipe,
Campos Helton,
Coimbra Cândido,
Natali Antônio,
PrímolaGomes Thales
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.993.18
Subject(s) - medicine , temperate climate , cannula , thermoregulation , endocrinology , zoology , surgery , biology , ecology
This study aimed at investigating the changes in brain temperature (T b ) in SHR subjected to acute physical exercise in temperate and warm environments. Adult male Wistar and SHR rats were subjected to implantation of an abdominal temperature (T a ) sensor and a guide cannula in the right frontal cortex, that allowed us to insert a themorresistor and measure T b . After recovery, the animals were familiarized to run on a treadmill, and then, in alternate days, they were subjected to two constant‐speed protocols until fatigue (temperate and warm environments). The tail skin temperature (T s ), T a and T b were recorded. In the temperate environment, the SHR group showed greater increase in T b compared with Control group from the 13 th min until the 35 th min, greater increase in T a from the 19 th min until the 52 th min, and lower tail skin temperature from the 13 th until the 21 th min of exercise. In the warm environment, the SHR group showed greater increase in T b from the 11 th until the 24 th min, and greater increase in T a from the 9 th min until the 36 th min. The SHR group exhibited lower physical performance compared with the Control group in temperate and warm environments. We conclude that during acute exercise in temperate and warm environments, hypertensive rats present greater increases in T b and T a . Fapemig, Capes, and Cnpq.