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Improvement in cardiac function 1‐week post gastric bypass surgery
Author(s) -
DeVallance Evan,
Lee Kyuwan,
Grogg Kristen,
LeMaster Kent,
Hull Robert,
Tabone Lawrence,
Rosati Kristen,
Quinlin Robert,
Moore Corey,
Brader Alan,
Frisbee Jefferson,
Chantler Paul
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.952.4
Subject(s) - medicine , cardiology , afterload , ejection fraction , ventricle , waist , cardiac function curve , diastole , weight loss , preload , blood pressure , obesity , heart failure , hemodynamics
Obesity is associated with increases in afterload causing remodeling and alterations in left ventricle (LV) function. This makes obese individuals at a greater risk of developing LV impairments and a higher risk of cardiac events. LV stiffness is common with obesity. This is reflected by hypertrophy in the LV myocardium. Gastric by‐pass an intervention for rapid weight loss is commonly implemented in individuals with obesity. We aimed to evaluate the changes in LV function after gastric bypass surgery via echocardiography. We found a reduction in body weight (pre: 132 ±6 to post: 125 ±5 Kg) and waist circumference (pre: 122 ±5 to post: 112 ± 3cm). These anthropometric changes were accompanied by improvements in LV function. Improvements in pump efficiency are shown by decreases in LV end‐systolic volume (pre: 66 ±4 to post: 55 ±3 mmHg) and LV ejection time (pre: 291 ±10 to post: 211 ± 30ms). Accompanied by an increase in early diastolic annular velocity (e': pre: 0.14 ±0.01 to post: 0.16 ±0.01 p<0.05) and a decrease in LV end diastolic pressure (E/e': pre: 5.9 ±0.7 to post: 4.8 ±0.7 p=0.06) suggesting LV destiffening and improved diastolic function. The significant weight lost after gastric by‐pass surgery causes quick improvement in cardiac function. This may be attributed to the loss of visceral adipose tissue and change in CV risk factors relieving some burden on the heart allowing for more efficient LV work