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Trends in Breast Lesions in Lagos, Nigeria: Changing or Static?
Author(s) -
Obadofin Omobolade,
Daramola Adetola
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.926.3
Subject(s) - medicine , breast cancer , incidence (geometry) , breast lumps , cancer , physics , optics
Breast lesions are one of the commonest lesions seen in many surgical pathology laboratories and most of these are benign. However about 1 in 4 are malignant. The age standardized incidence rate of breast cancer in Nigeria is relatively low compared to breast cancer rates in North America, but the morbidity and mortality is much higher.
Objective To analyze the trend in frequency of breast lesions over a 15 year period and determine if there are any significant changes in Lagos, SW Nigeria.
Method Records of all breast specimens received from January 1999 – December 2013 were retrieved and analyzed. The 15 years were divided into 3 time periods: 1999‐2003, 2004‐2008 and 2009‐2013.
Results 34,084 biopsies were received over the 15 years of which 5,599 were breast specimens which accounted for 14.9, 18.8 and 16.0% of total biopsies in the 3 time periods respectively. Benign breast lesions (BBL) constituted 77.6, 76.3 and 64.6%, while malignant breast lesions (MBL) accounted for 22.4, 23.7 and 35.4% respectively. This shows a progressive decrease in the ratio of BBL to MBL. The decrease is more significant in the last 5 years (2009‐2013).
The peak age for BBL was consistently in the 3rd decade while that for MBL was the 4th decade in the 1999‐2003 time period then changed to the 5th decade for the latter 2 time periods.
2.7% of the breast biopsies were males'. Of these, 75% were BBL while 25% were MBL. Over the 3 time periods, MBL constituted 35.6, 25.5 and 16% of male breast lesions and 30, 23.6 and 35.9% of female breast lesions.
Conclusion Over the last 15 years, the proportion of MBL to BBL has increased; the peak age for BBL has remained the 3rd decade while that for MBL has increased from the 4th to the 5th decade. However, the proportion of MBL to BBL in males has decreased whereas this proportion has increased in females.