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The prevalence and associated factors of diabetes in pulmonary tuberculosis patients in rural China
Author(s) -
Cai Jing,
Ma Aiguo,
Wang Yu,
Wang Qiuzhen,
Han Xiuxia,
Zhao Shanliang,
Ma Yunbo
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.902.13
Subject(s) - medicine , underweight , overweight , pulmonary tuberculosis , diabetes mellitus , obesity , risk factor , tuberculosis , odds ratio , endocrinology , pathology
The co‐morbidity of diabetes (DM) and pulmonary tuberculosis (PTB) represents a double burden with significant public health implications. We conducted this study to determine the current prevalence of DM and identify the factors for the presence of DM among PTB patients in rural China. We selected 5146 newly‐diagnosed PTB patients (蠅18 years) registered in county PTB clinics from September 2010 to March 2013 in rural area of Shandong province, China, meanwhile 3744 non‐PTB residents living in the same community as the controls. A structured questionnaire were administered including BMI. The prevalence of DM in PTB patients (6.0%) was higher than in controls (5.0%, P<0.05). PTB patients had higher odds of having DM compared with controls (adjusted OR=1.31, 95% CI: 1.07–1.59). Then participants were divided into 4 groups based on whether the fasting plasma glucose was higher than 6.1 mmol/L in PTB cases or controls: PTB+DM group, PTB group, DM group and non (PTB+DM) group. We found that BMI of PTB+DM and PTB groups were significantly lower than the other groups (P<0.05), and underweight was risk factor but overweight was protective factor. Rate of current smoking was similar between PTB+DM (22.9%) and PTB group (23.5%), which was higher than the other groups (P<0.05). Furthermore, current smoking was positively associated with PTB group (OR=1.27, P=0.000). In conclusion, the prevalence of DM in PTB patients was higher than non‐PTB controls. While we confirmed beneficial effect of underweight and smoking in higher DM prevalence, and overweight was somewhat protective in co‐morbidity of PTB and DM. Supported by NSFC‐81172662.