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Infant Weight Gain in Week 1 and Body Mass Index at Age 2: A Prospective Cohort Study in an Urban Population
Author(s) -
Burnham Laura,
Merewood Anne,
Torjman Marc,
Chen Ning,
Grossman Xena,
Matlak Stephanie,
FeldmanWinter Lori
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.901.21
Subject(s) - medicine , overweight , body mass index , percentile , prospective cohort study , weight gain , weight change , pediatrics , population , cohort , obesity , cohort study , demography , weight loss , body weight , environmental health , statistics , mathematics , sociology
Objective Determine if change in weight in week 1 of life and feeding type in week 1 and month 1 of life were associated with BMI蠅85th percentile at 2 years. Methods: Newborns enrolled into a prospective cohort study at an urban hospital from 2008‐2012. We recorded all feeds during week 1 of life and assessed feeding at weeks 2, 3, and 4 with 24‐hour recall. We weighed and measured infants at birth, 7 days, and 2 years. At 2 years, we categorized children with BMI˂85th percentile as normal weight, and BMI蠅85th percentile as overweight. Results: There was a significant association between change in weight during week 1 and BMI at 2 years. In the multivariate analysis, infants gaining 蠅100g in week 1 were 2.5 times more likely to be overweight at age 2 compared to those who lost weight (p=.02). We found a significant association between feeding type and change in weight during week 1. Mean change in weight for exclusively breastfed infants was ‐7.7g and 53.57g for infants receiving any formula (p=.01). There was no significant association between feeding type at 1 week or 1 month and BMI at 2 years. Conclusions Weight gain of 100g or more during week 1 was associated with BMI>85th percentile at age 2. Infants receiving exclusive breast milk in week 1 gained less weight than formula feeders. Funding: National Research Initiative Grant