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Introducing the Comparative Atlas of Vertebrate Embryology Online Database
Author(s) -
Sedlmayr Jayc,
Cork R John,
Schachner Emma,
Rehorek Susan,
Smith Timothy,
McNulty Margaret,
Ziermann Janine,
Thorn Caitlin,
Diogo Rui
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.867.19
Subject(s) - vertebrate , biology , comparative anatomy , cave , chondrichthyes , embryology , anatomy , zoology , ecology , gene , biochemistry
The Comparative Atlas of Vertebrate Embryology (CAVE) is designed as common resource for the diverse research community of vertebrate biology and a complement to the Virtual Human Embryo (VHE) database. Initially, CAVE will focus on generating an online database containing data on hard and soft tissues of stages comparable to human (Carnegie) stages 6 to 23 (early embryo to early fetus) of the following evolutionarily significant taxa: Raja (Chondrichthyes), Ambystoma (Lissamphibia), Alligato r (Diapsida); and Microcebus and Tarsier, primates for comparison with our own genus. This database includes textual descriptions, tables, labeled histological sections, µCT and MRI scans, 3D reconstructions, and whole mount antibody staining with focus on developing muscles, organs, vasculature, and nervous system. CAVE will eventually serve as a central source for students, teachers and researchers engaged in various projects, and a unique source for evolutionarily based, question driven research. We will include already archived data: linking to existing online databases and cataloging and digitizing existing collections from around the world. CAVE will be parallel to the VHE and comparisons with humans will provide new and multidisciplinary insights into human evolution, health and disease.