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Cardiac vagal modulation changes from supine to active standing correlations with age in healthy sedentary and physically active subjects
Author(s) -
Soares Pedro Paulo,
Rodrigues Gabriel,
Gonçalves Thiago
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.827.6
Subject(s) - supine position , medicine , heart rate variability , heart rate , orthostatic vital signs , cardiology , blood pressure
The purpose of the present study was to correlate the adjustments in the cardiac autonomic modulation caused by active standing from supine (SUP) to the orthostatic position (ORT) with age in healthy subjects. Volunteers were 55 individuals (33 men) from 19 to 69 years old, participating or not in programs of physical activities. Heart rate (HR) was recorded beat‐by‐beat during 10min at SUP and ORT. In the frequency domain the high (HF, 0.15 ‐ 0.40Hz) and low‐frequency (LF, 0.04‐0.15 Hz) components were presented in normalized units and in the time domain as the mean of R‐R intervals (RR) and the root mean square of sucessive differences in the R‐R times series (rMSSD). In SUP R‐R (958.70 ± 165.00 ms, r= ‐0.09, p= 0.48) and LF (51.02 ± 16.37 n.u, r= 0.01, p= 0.90) did not demonstrated significant correlation with age. On the other hand, HF (39.64 ± 17.11 n.u, r= ‐0.30, p= 0.02), rMSSD (50.50 ± 30.74 ms, r= ‐0.5020, p<0.001) in SUP, and HF (468.4 ± 429.3 n.u, r= 0.66, P<0.001), R‐R (784.5 ± 132.5 ms, r= 0.32 p= 0.01), LF (69.63 ± 15.00 n.u, r=‐0.38, p<0.01) and rMSSD (24.85 ± 15.76 ms, r= ‐0.34, p< 0.01) in ORT were significant with age. When the changes from SUP to ORT were considered, ΔHF (‐20.47 ± 15.66 n.u, r= 0.52, p< 0.001), ΔLF (18.27 ± 16.57 n.u, r= ‐0.40, p< 0.01), ΔR‐R (39.64 ± 17.11 ms, r= ‐0.30, p= 0.02), ΔrMSSD (‐25.33 ± 26.02 ms, r=0.48, p< 0.001) were all correlated to age. The change in body position from supine to active standing provoked autonomic adjustments that better describe the associations between autonomic markers and age in a group of healthy volunteers from young to old adults, participating or not in physical activity programs.