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Influence of Ischemia on Peripheral and Central Fatigue During Handgrip Exercise
Author(s) -
Broxterman Ryan,
Wilcox Samuel,
Craig Jesse,
Jia Chen,
Warren Steven,
Barstow Thomas
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.824.19
Subject(s) - medicine , peripheral , cardiology , blood flow , vascular occlusion , physical exercise , ischemia , physical therapy
We hypothesized that both ischemic exercise and recovery would significantly increase peripheral and central fatigue. Subjects performed constant power handgrip exercise tests to exhaustion (TTE) at 80% peak power under control blood flow (Con), control blood flow + 5 min post‐exercise occlusion (Con + Occ), occluded blood flow (Occ), and occluded blood flow + 5 min post‐exercise occlusion (Occ + Occ) condtions. Peripheral and central fatigue was assessed via potentiated doublet twitch force (Q tw ), MVC, and voluntary activation (%VA). TTE was significantly different between Con and Occ exercise conditions, but was not significantly different within each exercise condition (Con: 480 ± 143 s; Con + Occ: 446 ± 165 s; Occ: 142 ± 25 s; Occ + Occ: 134 ± 25 s). Pre‐exercise Q tw , MVC, and %VA were not significantly different across conditions. Q tw and MVC were significantly lower post‐exercise in all conditions. Post‐exercise Q tw and MVC were significantly lower for Con + Occ, Occ, and Occ + Occ compared to post‐exercise Con Q tw . %VA was significantly reduced post‐exercise for Occ and Occ + Occ. The current findings suggest that ischemic exercise and recovery augment both peripheral and central fatigue.