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Prevalence of Sarcopenia in Acutely Hospitalized Older Adults
Author(s) -
Deer Rachel,
Goodlett Shawn,
Volpi Elena
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.815.10
Subject(s) - sarcopenia , medicine , cohort , grip strength , gerontology , physical therapy , cohort study , older people , geriatrics , psychiatry
Debate is ongoing as how to best define and measure sarcopenia. Several operative definitions have been published by international consensus panels over the past few years. In the absence of standard clinically relevant cutpoints studying the prevalence of sarcopenia had been difficult. Additionally, the prevalence of sarcopenia in vulnerable populations (acute/chronic illness, multiple comorbidities) has not been investigated. We examined the prevalence of sarcopenia using three operational definitions (Foundation of NIH Sarcopenia Project (FNIH), International Working Group Sarcopenia Initiative (IWGS), and European Working Group on Sarcopenia in Older Persons (EWGSOP)) in a cohort of older adults (n=42, >65 yrs) hospitalized for an acute disease in the Acute Care for the Elderly unit at UTMB. We measured body composition, grip strength, and gait speed. The prevalence of sarcopenia in our cohort of acutely hospitalized older adults was higher in men than women according to all 3 operational definitions. FNIH yielded the lowest prevalence (25% men, 13% women), while prevalence was identical and significantly greater using IWGS and EWGSOP criteria (58% men, 40% women). There was moderate agreement between FNIH criteria and the other criteria in men (43%) with less agreement in women (17% ‐ 25%). Agreement between all methods for absence of sarcopenia was high (>89%). Agreement between the IWGS and EWGSOP definitions, both positive and negative, was >92%. In conclusion, the prevalence of sarcopenia in acutely ill hospitalized older adults varies greatly depending on which consensus definition is used for diagnosis (10% ‐ 58%). Dairy Research Institute (1229) and UTMB Claude D. Pepper OAIC (5P30‐ AG024832).