Premium
Assessment of Human Physiological Oscillations with Interferometry
Author(s) -
Haselby Cyrus,
Smith Jillian,
Murphy Robert,
Heinking Kurt,
Henderson Kyle
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.799.1
Subject(s) - qrs complex , expiration , heart rate , cardiac cycle , physics , medicine , heartbeat , cardiology , anatomy , blood pressure , respiratory system , computer science , computer security
A helium neon laser interferometer uses the constructive and destructive interference properties of light to measure motion <1µm. Assessment of subtle physiological oscillations would help validate the field of Cranial Osteopathy in which palpated cranial motion is used to assess patient well‐being. A two‐sided interferometer was designed to measure cranial expansion and contraction at the temporal bones. A data acquisition system (iWorx) recorded systemic vitals at a rate of 20,000 samples/sec. A 1:58 min recording contained 107 heart beats, 28 respirations, and 5 cycles of cranial motion. Fringe waves, equivalent to 0.32µm of motion, revealed 8‐9 distinct periods of cranial motion per cardiac cycle. Based on the timing of the ECG and Wiggers diagram the four periods following the QRS were examined for potential mechanistic relationships. The first period immediately after the QRS resulted in 13.9±0.3µm of cranial motion and was not influenced by respiration. The other three periods, occurred from prior to the T‐wave to after the T‐wave, resulted in cranial motion of 5.4±0.4µm, 20.3±0.2µm, and 13.0±0.3µm; N=107 heart beats. During expiration, the frequency of these fringe waves was significantly greater (P<0.001). Animal studies are needed to validate which cardiovascular mechanism contributes to each period of cranial motion. Conclusion these data demonstrate that interferometry can be used to detect subtle cranial motion that corresponds to cardiac output and respiratory rate.