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Vitamin D in Serum of Non‐Pregnant, Pregnant and Lactating Rhesus Monkeys
Author(s) -
Preston Alan,
Rodriguez Idia,
Maldonado Elizabeth,
RodriguezOrengo Jose
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.756.1
Subject(s) - lactation , pregnancy , primate , vitamin , physiology , nonhuman primate , gestation , biology , vitamin d and neurology , endocrinology , medicine , genetics , neuroscience , evolutionary biology
Limited studies have been carried out on the level of vitamin D in non‐human primates. Herein, we present data using the preferred vitamin D indicator, serum 25‐OH vitamin D, sequentially collected from female Rhesus monkeys during stages of non‐pregnancy, pregnancy, lactation and return to non‐pregnancy. To minimize number of variables, all animals were of similar age (7 ‐9 yrs), housing type (specific pathogen‐free cages) and diet fed (Teklad NIB Primate Diet containing 8000 IU/kg vitamin D 3 ). Serum 25‐OH vitamin D was quantified using HPLC. Circulating levels were shown to be well in excess of human which might be expected due to the diet. Preliminary findings from 10 animals show wide variations of serum levels among animals with no well defined pattern established during the period of pregnancy and lactation. Increasing the number of animals should help resolve this problem. Once reliable baseline information is obtained, future work can be carried out examining other aspects of non‐human primate physiology.