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Effects of Telephone Intervention on Inflammatory Cytokines Following Summer Lifestyle Intervention Program
Author(s) -
Solis Leslie,
Ponte Luis,
Martinez Diego,
Park Daniel,
Park KyungShin
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.677.3
Subject(s) - adiponectin , medicine , overweight , obesity , intervention (counseling) , physical therapy , insulin resistance , psychiatry
Inflammatory cytokines are useful biomarkers in predicting developing diseases in adulthood like cardiovascular disease and may be positively affected by physical activity and weight loss, but may regress without follow‐up intervention. PURPOSE To determine the effects of a 10 month telephone follow‐up after an 8 week summer lifestyle intervention (SLI) on inflammatory cytokines, body composition and physical fitness in obese Hispanic children. METHODS 41 overweight or obese students (9‐14yrs) participated in 8 week SLI. After summer camp, students were randomly assigned to two groups: 10 month follow‐up telephone intervention (TI) and control (CON). Blood samples were obtained before (PRE), a week after (POST) and 10 months following the 8 week summer intervention (YEAR) to measure levels of TNF‐α, CRP, and adiponectin. RESULTS 8 weeks of SLI significantly improved levels of inflammatory cytokines (P values: PRE vs. POST for all variables were < .03) in both groups. While the improvement in CON returned to PRE values during follow‐up period, TI statistically maintained changes up to 10 months with follow‐up telephone intervention: TNF‐α (PRE:62.7±1.34pg/mL®POST:48.6±1.42®YEAR:53.4±1.25, Mean±SE , P value: PRE vs. YEAR=.0034), CRP (594.6±90.8ng/mL®415.2±102.1®498.3±101.3, P=.022), and adiponectin (8.9±1.47ug/mL®11.4±1.7®10.7±1.6, P=0.046). CONCLUSION 8 weeks of SLI reduced levels of TNF‐α and CRP while elevating levels of adiponectin in Hispanic children. Results indicate that telephone intervention is an effective secondary medium in maintaining changes of inflammatory cytokines obtained from intensive treatment.