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Metabolic Syndrome (MetS) in an HIV Cohort on Antiretroviral Therapy (ART)
Author(s) -
Lopez Johanna,
Tiozzo Eduard,
Konefal Janet,
Adwan Sarah,
Martinez Lynell,
Villabona Juan,
Cutrono Stacey,
Rodriguez Allan,
Woolger Judi,
Lewis John
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.595.18
Subject(s) - medicine , metabolic syndrome , waist , cohort , glycemic , diabetes mellitus , socioeconomic status , population , human immunodeficiency virus (hiv) , gerontology , obesity , environmental health , endocrinology , immunology
Objective The purpose of this study was to evaluate the prevalence of MetS characteristics, and factors associated with the presence of MetS, in 89 people living with HIV (PLWH) on ART enrolled in a community‐based exercise training and nutrition education program targeting individuals of low socioeconomic status. Results One in three PLWH met Adult Treatment Panel (ATP) III criteria for MetS and it was mostly due to high waist circumference and elevated blood pressure. Higher use of protease inhibitors, elevated hemoglobin A1C (HbA1c), greater self‐reported daily caloric intake and consumption of carbohydrates, sugar, added sugar, and higher glycemic load were found among the individuals with MetS, compared to those without it. Elevated HbA1c and high total sugar consumption were the strongest predictors and accounted for 30% of the occurrence of MetS. Conclusions The overall prevalence of MetS observed was higher than previously reported in the general population and other PLWH cohorts. Additional work is needed to determine whether MetS is a more disease/treatment or lifestyledependent condition in PLWH. This material is based on work supported by AstraZeneca HealthCare Foundation's Connections for Cardiovascular Health SM ( CCH ) program.