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Dietary Quality in Nulliparous Women Planning Pregnancy: Results from the ISIS Study
Author(s) -
Hsiao Pao Ying,
Fung June,
Mitchell Diane,
Hartman Terryl,
Goldman Marlene
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.590.8
Subject(s) - pregnancy , medicine , logistic regression , odds ratio , obstetrics , prospective cohort study , body mass index , odds , cohort , cohort study , gestation , gynecology , biology , genetics
There is evidence that periconceptional health, including dietary quality (DQ), may affect conception and pregnancy outcome. We evaluated the association between DQ, as assessed by the Alternative Healthy Eating Index for Pregnancy (AHEI‐P) and conception and pregnancy outcomes in participants of the ISIS study, a prospective cohort study of healthy, nulliparous women (n = 132) who were planning their first pregnancy (mean age = 29.8 ± 3.2 y and BMI = 24.3 ± 5.4 kg/m 2 ). Dietary data were collected prior to conception using a series of three unannounced, telephone 24‐hour dietary recalls. Outcomes of interest included confirmed clinical pregnancy (CCP; hCG 蠅 20 mIU/mL), live birth (LB), and pregnancy loss (PL). Of the 80 CCP, 69 were LB and 11 were PL. Mean AHEI‐P was 72.0 ± 13.8. When AHEI‐P was categorized into tertiles, 59%, 55% and 68% of the participants in the tertiles (from lowest AHEI‐P to highest and most favorable) achieved CCP. Preliminary data analyses, using logistic regression, revealed that after controlling for maternal age, race, smoking status, pre‐pregnancy BMI, and time to conceive, there was a greater odds of achieving CCP for every 5‐point increase in AHEI‐P score (OR: 1.27; 95% CI: 1.06‐1.52). No significant association was found between AHEI‐P and LB or PL. Results of this study suggest differences in DQ and likelihood of CCP. Future analyses will examine the role of paternal DQ on pregnancy outcomes. Supported by R01 HD409762 from the Eunice Kennedy Shriver NICHD.