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Parameters of Metabolic Syndrome in a Healthy Population could be Related to Diet, Activity Level and Family History
Author(s) -
VergaraJimenez Marcela,
Missimer Amanda,
DiMarco Diana,
Murillo Ana,
Brodeur Melanie,
Andersen Catherine,
Fernandez MariaLuz
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.588.12
Subject(s) - blood pressure , medicine , endocrinology , family history , zeaxanthin , metabolic syndrome , population , waist , cholesterol , diabetes mellitus , diastole , lutein , obesity , carotenoid , biology , biochemistry , environmental health
We recruited 24 men and 26 women (18‐30 y) to evaluate whether family history, activity, or diet would influence the number of metabolic syndrome (MetS) parameters in this population. The mean values for plasma triglycerides (72.5 ± 29.9 mg/dL), HDL‐cholesterol (64.9 ± 18.9 mg/dL), glucose (92.2 ± 6.6 mg/dl), systolic (112.0 ± 12.4 mm Hg) and diastolic blood pressure (72.9 ± 7.0 mm Hg) and waist circumference (81.4 ± 6.5 cm) were within a healthy range. However, 16% of individuals (n=8) had one and 6% (n=3) had two parameters of MetS, with elevated plasma glucose and high blood pressure being the most consistently observed. Of the 11 subjects, 8 were male and 3 female. Family history indicated that 60% of the participants could be at risk for cancer, 46% for heart disease, and 38% for diabetes. For the female participants, low HDL‐cholesterol was related to a history of cancer, and high blood pressure correlated with history of heart disease in male participants. Number of active minutes/week was negatively correlated with LDL‐cholesterol (r = ‐0.339, P < 0.05) and triglycerides (r = ‐0.41, P < 0.01), whereas HDL‐cholesterol was positively correlated with intake of the carotenoids, lutein and zeaxanthin (r = 0.339, P < 0.05) and diastolic blood pressure correlated negatively with dietary beta‐carotene (‐0.316, p< 0.05) and dietary lutein and zeaxanthin (r= ‐0.307, P < 0.05). These results suggest that increased physical activity and a diet high in antioxidants favorably affect the parameters of MetS in this population, which may help protect against familial history of chronic disease