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Older African‐American Men Have Higher Risk for Cardiovascular Disease Compared to Women, Based on the Diabetic Indicators Prediction
Author(s) -
Carter Ashley,
Ilich Jasminka,
Ralston Penny,
YoungClark Iris
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.588.11
Subject(s) - medicine , blood pressure , diabetes mellitus , confounding , anthropometry , framingham risk score , population , marital status , disease , demography , gerontology , endocrinology , environmental health , sociology
African‐Americans (AA) have disproportionately higher risk of developing diabetes and cardiovascular disease (CVD) compared to other ethnicities. Various factors play role in the development of either one of the diseases. Our objective was to assess diabetes indicators in relation to CVD risk factors in AA adult women and men, taking into account possible confounders. Participants (n=79, 69% were women) were mid‐life and older AAs, 59.3±9.2 y (mean±SD), BMI 34.7±8.3 kg/m 2 , recruited from North Florida churches. Anthropometrics and blood pressure were measured in standard fashion. Fasting serum was analyzed for glucose, insulin, lipid profile, Apo A1 and B. CVD Risk Scores for each participant were determined using the Framingham and American Heart Association Assessments. The diabetes indicators HOMA‐β and HOMA‐IR were also assessed. In the regression analyses, the confounders of gender, education, marital status, current smoking, perceived health, medication use, physical activity, and dietary intake were taken into account. There were no difference in age, BMI and blood pressure between women and men. Men had higher energy intake and blood glucose but lower HDL compared to women (p<0.05). In the total population, HOMA‐β and HOMA‐IR were significantly (p<0.05) correlated with LDL and diastolic blood pressure, respectively. Based on the CVD Risk Assessments, men were significantly (p<0.05) more likely to develop heart disease than women. Overall, the results suggest that diabetes could be an important indicator for CVD risk, particularly in AA men.