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Imaging Functional Dynamic Processes within Integral Membrane Proteins at the Single‐Molecule Scale
Author(s) -
Blanchard Scott,
Terry Daniel,
Munro James,
Akyuz Nurunisa,
Gregorio Glenn,
Kolster Rachel,
Zhou Zhou,
Zhao Hong,
Altman Roger,
Juette Manuel,
Zheng Qinsi,
Jockusch Steffen,
Boudker Olga,
Mothes Walther,
Javitch Jonathan
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.498.3
Subject(s) - context (archaeology) , integral membrane protein , nanotechnology , function (biology) , scale (ratio) , membrane , computer science , biological system , chemistry , membrane protein , physics , materials science , biology , biochemistry , microbiology and biotechnology , quantum mechanics , paleontology
Advances in single‐molecule imaging and fluorescence technologies now enable direct insights into functional dynamic processes in diverse families of integral membrane proteins. These data pave the way for quantitative descriptions of function from the intuitive perspective of time‐dependent changes in structure. Challenges on this road will be discussed in the context of recent advances in the field.