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Prepregnancy Body Mass Index is an Independent Risk Factor for Pregnancy Complications and Poor Birth Outcomes
Author(s) -
Shin Dayeon,
Song Won
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.272.7
Subject(s) - medicine , underweight , body mass index , obstetrics , gestational diabetes , pregnancy , birth certificate , gestational age , birth weight , small for gestational age , gestational hypertension , odds ratio , live birth , weight gain , risk factor , gestation , overweight , population , body weight , environmental health , biology , genetics
Pregnancy complications and poor birth outcomes represent public health burden with serious consequences to both mothers and infants. Public health burdens can be reduced by achieving gestational weight gain (GWG) guidelines, which are dependent on prepregnant weight status (ppg‐BMI). We examined if ppg‐BMI alone is a risk factor for gestational hypertension, gestational diabetes, preterm labor, and birth of small‐for‐gestational‐age (SGA) and large‐for‐gestational‐age (LGA) infants. Included in this study are the data of 219,868 women from 2004‐2011 PRAMS which were from the state birth certificate file plus self‐administered questionnaires. Multivariate logistic regression analyses were performed to examine if ppg‐BMI was associated with pregnancy complications and poor birth outcomes after controlling for gestational weight gain, maternal age, race/ethnicity, education level, marital status, gestational age at birth, participation in WIC, and smoking during pregnancy. The IOM's GWG guidelines were achieved inadequate, adequate and excessive by 23%, 29% and 48%, respectively. Even after GWG was controlled, compared to normal ppg‐BMI (18.5–24.9 kg/m 2 ) group, women with obese ppg‐BMI (蠅30 kg/m 2 ) had increased adjusted odds ratio (AOR; 95% CI) of gestational hypertension (2.91; 2.76–3.07), gestational diabetes (2.78; 2.60–2.96), and LGA infants (1.87; 1.76–1.99), whereas underweight ppg‐BMI group (<18.5 kg/m 2 ) had increased odds of preterm labor (1.25; 1.16–1.36) and SGA infants (1.36; 1.25–1.49), but decreased odds of LGA infants (0.72; 0.61–0.85). Preconception care of reproductive aged women is as important as prenatal care during pregnancy to lower the risk of pregnancy complications and adverse birth outcomes.