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Micronutrient Status of Pre‐Bariatric Surgery Patients: the Prevalence of Rare and Poly‐micronutrient Deficiencies and Relationships with Pre‐Surgery BMI?
Author(s) -
Crowley Nina,
Petitpain Debbie,
DellaValle Diane
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.254.8
Subject(s) - micronutrient , cohort , medicine , incidence (geometry) , micronutrient deficiency , vitamin b , vitamin , cohort study , gastroenterology , surgery , pediatrics , pathology , physics , optics
Adequate micronutrient (MN) status plays a direct role in post‐bariatric surgery (BS) outcomes. The goal of this cross‐sectional analysis was to examine the prevalence of MN deficiencies in a cohort of patients preparing for BS (n=119; 87%F; 41.9±11.4y; 54.1±13.1 kg/m 2 ). Prior to BS, in addition to routine lab work (Fe, B 12 , vitamin D, folate), serum levels of Zn, Cu, B 1 , and B 6 were assessed. Sub‐optimal levels of vitamin B 6 were observed with the most frequency (70.6% of the cohort), followed by vitamin B 1 (35.3%), Zn (15.1%), and Cu (2.5%). Incidence of pre‐surgical B 6 deficiency was negatively correlated with low Zn (r=‐0.24, p=0.008) and low B 1 status (r=‐0.37, p<0.001). Seventy nine percent of the cohort exhibited a deficiency in one of the routine MNs (e.g. Fe, B 12 , vitamin D, folate) in addition to one of those pilot‐tested (Zn, Cu, B 1 , B 6 ). Fifty‐two percent of the cohort had their BS delayed in order to address MN deficiencies. Patients with BMIs >51.9 kg/m 2 were significantly more likely to have multiple MN deficiencies, as well as B 1 deficiency compared to those with BMIs<51.9 (p=0.01 and p=0.04, respectively). Current practice guidelines for assessing nutrition status in BS patients do not recommend routine assessment of Zn, Cu, B 1 , and B 6 . This study clearly indicates a significant prevalence rate of sub‐optimal MN status in the BS candidate, and further research is needed to explore how this may impact post‐surgical outcomes.