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High fidelity biopotential recordings in mice using a novel telemetry implant
Author(s) -
Guild SarahJane,
Lau Sien Yee,
Russell David,
McCormick Daniel,
Cuddy Helen,
Budgett David,
Kondo Masahiro,
Malpas Simon
Publication year - 2015
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.29.1_supplement.1041.1
Subject(s) - telemetry , biomedical engineering , computer science , battery (electricity) , implant , wireless , high fidelity , biotelemetry , computer hardware , medicine , power (physics) , electrical engineering , engineering , telecommunications , surgery , physics , quantum mechanics
We have developed a fully implantable telemetry device for use in mice. The telemeter is able to measure biopotential signals (EEG, EMG, ECG) at a sampling rate of 2000 Hz. The device has a volume of 1.45 cc with a unique contour design for subcutaneous implantation in mice over 20 gm in weight. A novel aspect to the device is that it contains no battery. Power to run the telemeter is provided by a wireless power pad placed under the cage of the animal. This provides continual operation of the telemeter (>90% data collection in a 24 hour period) during a range of normal animal behaviours. We have assessed the ability of this device to record biopotential signals for up to 3 months. We believe this technology offers new experimental paradigms to be explored.