Premium
Vitamin D Status and its Correlation with Blood Pressure Among Saudi Postmenopausal Women: A Cross‐Sectional Study (LB755)
Author(s) -
Al Marhoumi Lujain,
Al Kadi Hanan
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.lb755
Subject(s) - medicine , vitamin d and neurology , vitamin d deficiency , blood pressure , parathyroid hormone , anthropometry , cross sectional study , osteoporosis , population , diastole , endocrinology , physiology , gastroenterology , calcium , environmental health , pathology
The aim of the present study was to assess the correlation between vitamin D status and blood pressure (BP) in a group of Saudi postmenopausal women. METHODS: This cross‐sectional study was conducted in the “Center of Excellence for Osteoporosis Research” (CEOR), King Abdulaziz University (KAU), Jeddah, Saudi Arabia, from March‐May 2013. The study population included 31 Saudi women (52‐70 years old), randomly selected from “Primary Health Care Centers” in Jeddah, Saudi Arabia. Blood pressure was measured by a standardized method using an automated BP monitor (BPTru). Anthropometric measurements were obtained and fasting blood samples were collected. Serum 25‐hydroxyvitamin D [25(OH) D] and parathyroid hormone (PTH) were measured by sandwich chemiluminescence immunoassay method. RESULTS: Vitamin D deficiency was highly prevalent among the study group with 68% of the women having levels <50 nmol/L and 39% having levels <25 nmol/L. In all women combined, 25(OH) D level was inversely associated with both systolic (r=‐0.39; P=0.028) and diastolic (r=‐0.39; P=0.030) BP. Blood pressure was higher in the group with severe vitamin D deficiency (<25 nmol/L), but this did not reach statistical significance. Linear regression analysis showed that 25(OH) D was independently and inversely associated with diastolic BP. CONCLUSION: In Saudi postmenopausal women, vitamin D deficiency is highly prevalent and 25(OH) D level was independently and inversely associated with diastolic BP. Correction of vitamin D deficiency in this high risk group is needed and may improve BP control in hypertensive postmenopausal women. Interventional studies to evaluate if attainment of optimal vitamin D status may prevent hypertension are necessary. Grant Funding Source : Supported by the Center of Excellence for Osteoporosis Research, King Abdulaziz University, Jeddah, Saudi Arabia