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High‐intensity interval exercise protects against postprandial endothelial dysfunction in obese adolescent males (LB662)
Author(s) -
Ryder Justin,
Hultgren Neil,
Barazza Estela,
Gaesser Glenn,
Shaibi Gabriel
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.lb662
Subject(s) - postprandial , medicine , endothelial dysfunction , meal , evening , brachial artery , morning , supine position , cardiology , endocrinology , insulin , blood pressure , physics , astronomy
In adults, consuming a high‐fat meal can induce endothelial dysfunction while exercise may mitigate postprandial endothelial dysfunction. Whether exercise is protective against postprandial endothelial dysfunction in youth is unknown. The purpose of this study was to determine if high‐intensity interval exercise (HIIE) performed the evening prior to a high‐fat meal protects against postprandial endothelial dysfunction in obese adolescent males. Fourteen obese adolescent males (BMI%tile=98.5±0.6; 14.3±1.0yrs; VO 2 peak=2.6±0.5 L/min) completed a single HIIE session on a cycle ergometer (8 X 2min at 蠅90%HRmax, with 2min active recovery between bouts, 42min total) in the evening. Participants returned at 09:00 the following morning where brachial artery flow‐mediated dilation (FMD) was measured using duplex ultrasound after 20min of supine rest in the fasted state. Following baseline FMD (7.5±3.0%), a high‐fat milkshake (; 60% Fat, 35% CHO) consisting of 0.7g/kg of body weight was consumed (766±84 kcal). FMD was subsequently measured at 2hr and 4hr post‐consumption. Despite consuming a high‐fat meal, endothelial function was preserved at 2hr (8.4±3.4%) and 4hr (8.8±3.9%) post‐meal (p (time) =0.598). These data suggest that HIIE may protect against the deleterious vascular effects associated with a high‐fat diet in obese adolescent males. Grant Funding Source : American College of Sports Medicine