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Examining Bone Density of the Mandibular Corpus: Clinical Implications in Osteoporosis (LB42)
Author(s) -
Khusid Johnathan,
Hartley Benjamin,
Caceres Noel,
Márquez Samuel
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.lb42
Subject(s) - osteoporosis , bone density , medicine , dentistry , mandible (arthropod mouthpart) , bone disease , bone mineral , condyle , dentition , orthodontics , biology , botany , genus
Osteoporosis is a ubiquitous disease, with a prevalence of 200,000,000 cases worldwide. In these cases, bone density is at least 2.5 standard deviations below the global mean. While this debilitating condition affects both genders, women are disproportionately afflicted due to post‐menopausal hormonal changes. Accordingly, fractures of the hip are a common cause of morbidity and mortality among females, and as such have been well documented. It is hypothesized that the hypoestrogenic state of post‐menopausal women will result in a lower bone density than that of their male counterparts. This investigation examined density changes in the lesser studied mandibular corpus as a function of age for each gender. The mandibular condyle was removed from 12 cadavers, obtaining mass and volume by digital scale and water displacement respectively, and the calculation of their densities. Our findings showed that bone density increased with increasing age (r = 0.47). However, when measures were subdivided by gender, bone density among women decreased with age (r = ‐0.09), while that of their male counterparts increased (r = 0.32). In addition, a significant correlation was also found between bone density and dentition status as defined by total number of natural, unaltered teeth (p<0.05). Further study of facial bone density among women may shed light on understanding risk factors for age related dental disease as it pertains with osteoporosis.