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Association between intake of fish and shellfish and omega‐3 (n‐3) fatty acids and cardiovascular disease (CVD) risk factors in middle‐aged female with type 2 diabetes (T2D). (LB343)
Author(s) -
Park Seokyung,
Lee Eun Jung,
Kim Soyeon,
Jang Won,
Kim Hyesook,
Choi Young Ju,
Huh Kap Bum,
Chang Namsoo
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.lb343
Subject(s) - fish oil , medicine , quartile , shellfish , type 2 diabetes , triglyceride , endocrinology , physiology , diabetes mellitus , cholesterol , biology , fish <actinopterygii> , confidence interval , fishery , aquatic animal
This study was aimed to examine the association between intake of fish and shellfish and n‐3 fatty acids and CVD risk factors in 356 middle‐aged (40‐64 years) female with T2D. Dietary food intake was assessed by semiquantitative food frequency questionnaire method. Multiple regression analysis showed that serum triglyceride level was negatively and HDL‐cholesterol positively associated with fish and shellfish and n‐3 fatty acids intake after adjusting for age and BMI. Right pulse wave velocity, atherogenic index and diastolic blood pressure were negatively associated with n‐3 fatty acids intake. The adjusted odds ratio (OR) for hypertriglyceridemia was lower in the 4th quartile compared to the 1st quartile of fish and shellfish intake (OR=0.474;95% CI=0.243‐0.924) and n‐3 fatty acids intake (OR=0.477;95% CI=0.242‐0.943). The OR for hypoalphalipoproteinemia was lower in the 4th quartile compared to the 1st quartile of fish and shellfish intake (OR=0.530;95% CI=0.289‐0.972) and n‐3 fatty acids intake (OR=0.468;95% CI=0.255‐0.861). These results suggest that intake of fish and shellfish and n‐3 fatty acids is associated with decreased CVD risk in middle‐aged female patients with T2D. Grant Funding Source : This research was supported by the Basic Science Research Program through the National Research Foundation of Korea (NRF) funded by the Ministry of Education (NRF‐2013R1A1A2011544) and Brain Korea 21 Plus.