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Embryology of extraocular muscles: a new vision (923.7)
Author(s) -
Tréchot Fanny,
Tonnelet Romain,
Micard Emilien,
Labrousse Marc,
Angioi Karine,
Braun Marc
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.923.7
Subject(s) - extraocular muscles , anatomy , embryology , trochlear nerve , primordium , oblique case , biology , medicine , philosophy , pathology , biochemistry , alternative medicine , gene , palsy , linguistics
Purpose : To describe the embryology of extraocular muscles through 3D viewing algorithm from Carnegie stage XVII to Carnegie stage XXIII (41st‐57th day of development). Materials and Method : The work consisted of a scanning and a data processing reconstruction of embryonic histological material. Material came from anatomical universities collections. 12 embryos were selected, and 7 were dedicated to muscle study (from 14.5mm to 54.5mm). This data processing has allowed a study in three spatial planes. Results : From stage XVII, all extraocular muscles are in place, including levator palpebrae. The study in 3 planes makes their individualization easier. Gilbert (Carnegie Institution) described the origin of inferior rectus and inferior oblique by a common primordium, however from the stage XVII the two muscles are clearly separated. The decussation of the superior oblique is seen from the stage XIX, the trochlea appears at stage XXII. Our work also demonstrates the nerves : optic, oculomotor, trochlear, trigeminal and abducens. The junctions between nerve and muscle are found, especially for the lower branch of the oculomotor nerve. Conclusion : This new study tool has resulted in explicit images of the development of extraocular muscles in the embryonic period. It helped to provide details with respect to the work already established by the Carnegie Institution.