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Low intensity resistance training promotes peripheral and central adjusts on cardiovascular control (881.6)
Author(s) -
Oliveira Larissa,
Macedo Fabricio,
Melo Vitor,
Mota Marcelo,
Silva Tharciano Luiz,
Fontes Milene,
Santana Michael Nadson,
Santos Robervan,
Barreto Andre,
Santos Márcio Roberto,
SantanaFilho Valter
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.881.6
Subject(s) - baroreflex , blood pressure , medicine , heart rate , cardiology , vascular resistance , anesthesia , endocrinology
The aim was to evaluate the effects of low intensity resistance training (RT) on blood pressure, cardiovascular autonomic balance and vascular reactivity. One group of animals were submitted to RT. Control animals (CO) were fictitious trained (no exercise). After 8 weeks of RT or fictitious exercise, blood pressure and pulse interval were recorded and mesenteric artery was removed and sliced in rings for vascular reactivity analysis (Acetilcholine (ACh): 10‐9 ‐ 10‐4 M; Nω‐nitro‐L‐arginine methyl ester hydrochloride (L‐NAME): 100µM). The variabilities of pulse interval, blood pressure and spontaneous baroreflex sensitivity (BRS) were analyzed. RT animals showed a reduction in mean arterial pressure (CO 117.04 ± 2.68 vs RT 105.5 ± 4.28), diastolic arterial pressure (CO 107.71 ± 2.95 vs RT 97 ± 3.42) and heart rate (CO 395 ± 7.1 vs RT 344 ± 13.25). In addition, it was seen in trained animals an increase in cardiac vagal modulation (LF/HF: CO 0.35 ± 0.08 vs RT 0.14 ± 0.03), BRS (CO 0.77 ± 0.01 vs RT 1.05 ± 0.1) and percentage of ACh‐induced relaxation of mesenteric arterial rings (pD2: CO 6.2 ± 0.1 vs RT 7.1 ± 0.1) and addition of L‐NAME reduced the ACh‐induced relaxation (CO 52.0 ± 3.2% vs RT 35.8 ± 3.7%). In conclusion, we observed that low intensity RT was able to promote beneficial cardiovascular adaptations mediated by central and peripheral adjustments. Grant Funding Source : Supported by CNPq Foundation (Brazil)