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Effect of exhaustive exercise on contrast sensitivity and neurovascular coupling (853.11)
Author(s) -
Yamaguchi Yuji,
Ikemura Tsukasa,
Miyaji Akane,
Hayashi Naoyuki
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.853.11
Subject(s) - cardiology , medicine , contrast (vision) , stimulation , blood pressure , physics , optics
Neurovascular coupling (NVC) is assessed as an increase response to a given visual stimulation in the blood flow velocity in the posterior cerebral artery (PCAv). To investigate whether the change in NVC with exhaustive exercise, if any, associates with contrast sensitivity, we measured the PCAv during rest and exercise in 13 healthy males while they performed a leg‐cycle exercise at 75% of maximal heat rate until exhaustion. NVC was estimated as the relative change in PCAv from the mean value obtained during 20 s of eye closing to the peak value obtained during 40 s of visual stimulation involving looking at a reversed checkerboard. The conductance index (CI) of the PCA was calculated by dividing PCAv by the mean arterial pressure. Contrast sensitivity was measured before and after the exercise. At exhaustion, PCAv response to visual stimulation significantly decreased from 16±1 (at rest; mean±SE) to 11±1%, while it significantly increased to 20±2% with a significant increase in CI response to visual stimulation at recovery period. Contrast sensitivity significantly improved after exhaustive exercise, compared to the resting baseline. These results suggest that NVC decreases by exhaustive exercise and overshoot after the exercise, and that contrast sensitivity increases by an exhaustive exercise, implying that NVC associates with a change in contrast sensitivity. Grant Funding Source : Supported by Kozuki Foundation