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The bronchial hyperactivity in children with pollinosis (834.9)
Author(s) -
Saparova L.,
Rozenson R.I.,
Abduldayeva A.
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.834.9
Subject(s) - hay fever , medicine , morning , asthma , evening , exacerbation , lung function , pediatrics , lung , physics , astronomy
Aim of the study was to develop an easy available technique of lung function monitoring in pollinosis patients to predict the clinical course of disease both in seasonal exacerbation period and during the winter remission. Material: We studied 98 children with pollinosis aged 6‐14 years. Peak flow (PF) parameters were studied 3 times per day, namely in the morning, lunch time and in the evening, from the first of April to 30th October. Patients’ history records included hay fever symptoms and peak flow data. The curves of PF were drawn for disease monitoring and prediction. Results: Analyzing the daily changes of peak expiratory flow parameters, we estimated that in children with hay fever sensibilization to Artemisia species without evident asthma symptoms already at the second season peak expiratory flow decreased by 15‐20% and during the third season decreased further by 30% from the best parameters of the first year. Most striking in our studies was the finding that after the pollination season especially in children with disease duration more than 3 years and who did not receive the specific immunotherapy the level of changes decreased, but the type of PF curve didn’t change. In prognosis the most important was the possibility of pollen asthma appeared in most children already during the second hay fever season and was easy predictable by “bad” peak expiratory flow curves ‐ second and third type.