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Low intake of dietary antioxidants is associated with oxidative stress in Omani adults newly diagnosed with type 2 diabetes (829.16)
Author(s) -
Waly Mostafa
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.829.16
Subject(s) - oxidative stress , medicine , type 2 diabetes , context (archaeology) , diabetes mellitus , obesity , population , physiology , type 2 diabetes mellitus , environmental health , endocrinology , biology , paleontology
Background: Recent epidemiological studies strongly indicate that low physical activity and a diet low in vegetables and fruits increased risk of type 2 diabetes (T2DM) among adults. Environmental insults induce oxidative stress that has been suggested to occur in the context T2DM pathology. The prevalence of T2DM in the Omani adults’ population is continuously increasing and has been linked to obesity and a sedentary life style. Although the protective role of dietary antioxidants in the pathogenesis of T2DM and oxidative stress has been investigated in Western populations, no study has been carried out in Omani adults with T2DM. Objective: The purpose of this study was to examine the status of dietary antioxidants and oxidative stress Omani adults newly diagnosed with T2DM. Methods: A case‐control study involved 200 Omani adults (100 patients and 100 age‐ and gender‐matched healthy controls). Several parameters were investigated, including dietary intake, physical activity level and biochemical assessments of dietary antioxidants and oxidative stress markers. Results: Among the studied subjects; there was no significant difference in the physical activity level, meanwhile low serum levels of dietary antioxidants, and oxidative stress indices were prevalent in patients with T2DM compared with controls. The oxidative stress insults levels were higher in subjects living in urban areas versus rural areas. Conclusion: Low intake of dietary antioxidants is associated with oxidative stress and collectively increasing the risk of T2DM among high risk groups of the Omani adults’ population.