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Glycemic load is positively associated with diastolic blood pressure levels during pregnancy: preliminary results from a prospective cohort study in Rio de Janeiro, Brazil (810.11)
Author(s) -
Vilela Ana Amélia,
Mendes Roberta,
FrancoSena Ana Beatriz,
Farias Dayana,
Rebelo Fernanda,
Rodriguez Camila,
Kac Gilberto
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.810.11
Subject(s) - medicine , pregnancy , prospective cohort study , obstetrics , cohort , blood pressure , biomarker , confounding , calorie , glycemic index , endocrinology , glycemic , gynecology , diabetes mellitus , biochemistry , chemistry , genetics , biology
Objective: To evaluate the association between dietary GL and systolic (SBP) and diastolic blood pressure (DBP) during healthy pregnancy. Methods: Prospective cohort of 155 healthy pregnant women followed at 6‐13th, 20‐26th and 30‐36th gestational weeks. Dietary GL was calculated from glycemic index, carbohydrate content, and frequency intake of selected foods, obtained from food frequency questionnaire applied in the 3rd trimester having the whole pregnancy as the time frame. SBP and DBP throughout pregnancy were the outcomes. Statistical analysis comprised multiple longitudinal linear mixed‐effect models adjusted for obstetric, socioeconomic, dietetic, and biomarker variables. Results: Mean SBP was 109.7, 107.9, and 111.3 (mmHg) and DBP was 66.6, 64.3, and 67.2 (mmHg) for the 1st, 2sd and 3rd trimester, respectively, and didn’t varied according to tertile of GL in the 3rd trimester (p>0.05). GL was not associated with SBP in the multiple model (β=0.237; 95%CI=‐0.16‐0.64; p=0.245). GL was positively associated with DBP (β=0.387; 95%CI=0.08‐0.69; p=0.015) after adjusting for confounders such as per‐capita family income, skin color, BMI, and calories. Conclusion: Dietary GL was positively associated with DBP changes during pregnancy. Grant Funding Source : Supported by: FAPERJ, CNPq, CAPES