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Chronic isometric strength training reduces anxiety‐like behavior in Wistar rats (684.15)
Author(s) -
Conceicao Rodrigo,
LaureanoMelo Roberto,
Almeida Claudio,
Pinto Guilherme,
Cortes Wellington
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.684.15
Subject(s) - isometric exercise , corticosterone , elevated plus maze , anxiety , open field , medicine , radioimmunoassay , endocrinology , hormone , psychiatry
The objective of this study was to assess the anxiety‐like behavior in rats subjected to isometric strength training. For this purpose, the animals were randomized into 2 groups (n=10): control group and trained, the trained rats undergone a 8 week of isometric strength training. At the end of the training period, the rats underwent a behavioral assessment in an open field test, elevated plus maze test and marble burying test. Then, the animals were euthanatized and blood was collected for determination of serum corticosterone by radioimmunoassay method. Statistical analysis was performed by t student test, considering the significant differences between means at p <0.05. According to the results, in the elevated plus maze, it was demonstrated that trained group had higher time spent in the open arms (302%, p = 0.007) and greater percentage of entries into the open arms (288%, p = 0.007). Moreover the serum levels of corticosterone were significantly lower in the trained group (41%, p = 0.005). Together, these results suggest that to isometric strength training improves anxiety regulation by engaging inhibitory mechanisms related to stress responses. Grant Funding Source : FAPERJ/CNPq