Premium
Assessment of body composition in IBD children by bioelectrical impedance, DEXA and isotopic dilution methods (640.8)
Author(s) -
Godin JeanPhilippe,
Ezri Jessica,
Marques Vidal Pedro,
Martin FrancoisPierre,
Nydegger Andreas
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.640.8
Subject(s) - bioelectrical impedance analysis , medicine , doubly labeled water , fat free mass , pediatrics , fat mass , energy expenditure , body weight , body mass index
Background: This study is part of a research program to characterize energy balance in children with inflammatory bowel disease (IBD). In this frame, assessment of body composition provides important information regarding disease status in children. However, body composition data are lacking for most pathological conditions and methods comparison provide a useful guide to clinicians. Aim: To determine the level of agreement between three different methods of body composition assessment among children with IBD. Method: The study was approved by the local Swiss Ethics committee. 16 IBD children (8 girls and 8 boys, mean age 14.7 ± 1.3 years) and 23 healthy children (9 girls and 14 boys, mean age 13.0 ± 2.1 years) completed the study. Fat‐free mass (FFM, in kg) was assessed by DEXA (only in IBD children), bioimpedance analysis (BIA) and double labeled water (DLW) method. Results: In IBD children, FFM (kg) was 35.4 ± 5.3 by BIA vs. 34.2 ± 5.3 by DEXA (paired t‐test: p=0.07) and 36.0 ± 5.9 by DLW (p=0.28 between BIA and isotopes; p<0.02 between isotopes and DEXA). In healthy children, FFM (kg) was 38.3 ± 10.7 by BIA, vs. 40.5 ± 12.3 by DLW (paired t‐test: p<0.01). For IBD children, regressions between BIA and DEXA showed a slope of 0.90, between DLW and DEXA a slope of 0.98 and between BIA and DLW a slope of 0.83. Conclusion: In children with IBD, assessment of FFM by BIA is a non‐invasive method and provides adequate results relative to DEXA and DLW measurements. Grant Funding Source : Supported by a Swiss grant