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Supplemental vitamin D enhances strength recovery after damaging exercise (634.2)
Author(s) -
Barker Tyler,
Schneider Erik,
Dixon Brian,
Henriksen Vanessa,
Weaver Lindell
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.634.2
Subject(s) - vitamin d and neurology , isometric exercise , medicine , endocrinology , placebo , vitamin , muscle weakness , cholecalciferol , skeletal muscle , pathology , alternative medicine
Low serum 25(OH)D associates with skeletal muscle weakness after a muscle damaging event. Although supplemental vitamin D increases serum 25(OH)D concentrations, it is unknown if supplemental vitamin D enhances strength recovery after a damaging event in humans. Reportedly healthy and modestly active adult males were randomly assigned to a placebo (n=13) or vitamin D (cholecalciferol, 4000 IU; n=15) supplement. Supplements were taken daily for 35‐d. After 28‐d of supplementation, one randomly selected leg performed an exercise protocol intended to induce muscle damage. Circulating chemistries (25(OH)D and alanine (ALT) and aspartate (AST) aminotransferases), single‐leg peak isometric force, and muscle soreness were measured before supplementation. Circulating chemistries, single‐leg peak isometric force, and muscle soreness were also measured before (immediately) and after (immediately, 1‐h [blood draw only], 24‐h, 48‐h, 72‐h, and 168‐h) the damaging event. Supplemental vitamin D increased serum 25(OH)D (p<0.05) and enhanced the recovery in peak isometric force 24‐h after the damaging event (p<0.05). Supplemental vitamin D attenuated (p<0.05) the immediate and delayed (48‐h, 72‐h, and 168‐h) increase in circulating biomarkers of muscle damage (ALT and AST) without ameliorating muscle soreness. We conclude that supplemental vitamin D enhances strength recovery after muscular insult.