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Relationship between left pulse wave velocity, atherogenic index and dietary nutrient density in middle‐aged female type 2 diabetes patients (628.26)
Author(s) -
Kim Soyeon,
Kim Hyesook,
Choi Young Ju,
Huh Kap Bum,
Chang Namsoo
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.628.26
Subject(s) - niacin , medicine , confounding , pulse wave velocity , type 2 diabetes , homocysteine , endocrinology , diabetes mellitus , logistic regression , nutrient , blood pressure , chemistry , organic chemistry
The objective of this study was to investigate the relationship between vascular complication risk factor such as left pulse wave velocity (PWV), atherogenic index (AI) and serum homocysteine (Hcy), folate and vitamin B 12 levels and to identify dietary factors related with that in type 2 diabetes female patients. A total of 366 female subjects with type 2 diabetes participated in this study (age 50 yrs and over). Dietary intake data was assessed by using semi‐quantified food frequency questionnaire. Left PWV was negatively correlated with serum folate and vitamin B 12 levels and dietary protein intake and positively correlated with serum Hcy level. AI was positively correlated with left PWV and serum Hcy level. Multiple regression analysis with covariates showed that left PWV was negatively associated with protein and niacin dietary nutrient density. AI was positively associated with carbohydrate dietary nutrient density and negatively associated with protein, fat dietary nutrient density. For the further analysis multiple logistic regression analysis after adjusting for confounding factors, there was a significant inverse association between above median intake of nutrients such as protein and niacin and serum Hcy level, left PWV and AI.