Premium
Designing 3D tactile protein models as an introduction to biology research (618.10)
Author(s) -
Tirone Janine,
Geritano Mariah,
Solomon Irene,
O'Neal Marvin
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.618.10
Subject(s) - coursework , grant writing , function (biology) , computer science , neuroscience , mathematics education , psychology , biology , library science , evolutionary biology
Technological advances in rapid prototyping provide an opportunity for students to understand structure‐function relationships in our three dimensional living world. We are currently examining the impact of a newly developed introductory biology laboratory (BIO207) in which undergraduates investigate Lyme disease by designing 3D tactile models of proteins. Assessments providing direct comparison between this new lab and the concurrent alternative introductory biology lab include CURE (Classroom Undergraduate Research Experience) pre/post survey data, matched exam questions between the two courses, and performance in future coursework. Success and growth of this course has led to the design of a BIO207 alternative for undergraduates interested in neuroscience. Using the cat pre‐Botzinger complex (which is the primary locus of respiratory rhythm generation) as a topical focus, students use high‐resolution structures from RCSB Protein Data Bank to print tactile models and research a structure‐function relationship in this CNS region. Grant Funding Source : Supported by HHMI 52006940