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Impact of resistance training on testosterone levels in individuals with moderate to severe chronic obstructive pulmonary disease (576.3)
Author(s) -
Kuzel Aaron,
Kaelin Mark
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.576.3
Subject(s) - medicine , testosterone (patch) , copd , quality of life (healthcare) , physical therapy , pulmonary disease , population , environmental health , nursing
Purpose: Individuals with chronic obstructive pulmonary disease (COPD) exhibit decreased airflow and loss of diffusion area in the respiratory tree. Furthermore, current research suggests that low testosterone is a significant risk factor for these individuals. As testosterone levels decrease, the number and intensity of disease exacerbations significantly increases. The purpose of this study is to determine the impact of resistance training on testosterone levels in patients with COPD. Methods: Bellarmine University’s Institutional Review Board approved the study in October 2013. Six individuals (1 male, 5 females) with moderate to severe COPD enrolled in an 11 week resistance training program. Average FEV1% and pack years of the subjects are 57 + 17 and 59.3 + 43.5, respectively. Subjects initial evaluation consisted of the Senior Fitness Test (SFT), the St. George’s Respiratory Questionnaire (SGRQ) and salivary assays of testosterone to determine baseline functional mobility, health related quality of life and free testosterone levels. Results : Initial evaluations revealed below average functional mobility in these subjects compared to their age‐related peers in the following tests: Chair Stand Test ‐ 21% + 0.14%, Arm Curl ‐ 7% + 0.14%, Back Scratch ‐ 14% + 0.35, 8ft Up and Go Test ‐ 22% + 0.15%, 6‐minute walk ‐ 22% + 0.33%. Scores for the SGRQ came in at 37.74 points higher than those reported by healthy respondents. At the time of submission, initial testosterone collection remains in progress. Conclusions: Results of the SFT and SGRQ clearly demonstrate impaired functional mobility and self‐reported quality of life in this population.