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Lipoic acid induced weight loss (575.6)
Author(s) -
SanchezCardenas Marina
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.575.6
Subject(s) - lipoic acid , overweight , weight loss , lipogenesis , oxidative stress , obesity , antioxidant , endocrinology , medicine , insulin , chemistry , gerontology , adipose tissue , biochemistry
Lipoic Acid Induced Weight Loss Over 1.4 billion adults worldwide are considered overweight or obese. Obesity occurs when a person’s body initiates a cycle in which glucose imbalances promote lipogenesis and increases oxidative stress which may cause certain diseases. Prior research has demonstrated that Lipoic Acid (LA) has the ability to act as an insulin mimic as well as an antioxidant. Its insulin mimic capabilities allow it to regulate glucose levels and its antioxidant potential may protect against oxidative damage. However, very little research has been done on its possible beneficial effects in combating obesity. This study aims to demonstrate how supplementation with LA assists in weight loss with no change in life style. The results showed a significant decrease in body mass (in weight) in mice supplemented with LA when compared to those that were not exposed to LA. This study proposes the initial steps to facilitating the prevention of obesity and its related health complications through supplementation. Grant Funding Source : Supported by Title V STEM