Premium
Effect of oral nutritional supplementation on cognitive status in community dwelling elderly with sarcopenia and malnutrition (124.3)
Author(s) -
Tian Min,
Hustead Deborah,
Mustad Vikkie
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.124.3
Subject(s) - sarcopenia , malnutrition , medicine , gerontology , cognition , intervention (counseling) , cognitive decline , cognitive impairment , population , physical therapy , dementia , environmental health , psychiatry , disease
Past research suggests that age‐related cognitive decline is associated with compromised nutritional and functional status. Much of this literature has focused on either institutionalized elderly or healthy community‐dwelling elderly. The purpose of this study was to determine whether oral nutritional supplementation (ONS) can improve cognitive status in community‐dwelling older adults with malnutrition and sarcopenia. Older adults (N=285; 65‐95 yrs) from 8 countries across Europe and North America completed a 24‐week ONS intervention trial. Sarcopenia was determined using the European Working Group on Sarcopenia in Older People (EWGSOP) definition. Cognitive status was assessed by Mini‐Mental State Exam (MMSE). MMSE scores did not change significantly in the overall study population. In a subgroup of malnourished, sarcopenic older adults who began the intervention with cognitive impairment (MMSE score 蠄 26, n = 74), MMSE scores significantly improved from baseline to 12 weeks ( p = 0.004) and from baseline to 24 weeks ( p = 0.03). These data demonstrated that in community elderly with malnutrition and sarcopenia, ONS maintained cognitive status and even improved cognitive status in the subgroup with cognitive impairment. Grant Funding Source : Supported by Abbott Nutrition