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Comparison of two techniques for measuring pulse wave velocity in children (1156.5)
Author(s) -
Philips Nicole,
Faught Brent,
Hay John,
Cairney John,
O'Leary Deborah
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1156.5
Subject(s) - pulse wave velocity , arterial stiffness , medicine , cardiology , transit time , blood pressure , pulse (music) , gold standard (test) , pulse wave , femoral artery , carotid arteries , mathematics , physics , detector , transport engineering , engineering , power (physics) , optics , quantum mechanics
Pulse wave velocity (PWV) is used as an indicator of arterial stiffness. Carotid‐femoral PWV is the gold standard method. However, femoral pressure is difficult to measure in children and therefore carotid‐toe PWV has been used as an alternate method. Furthermore, measurement of carotid artery pressure requires highly skilled technicians, while participants are required to remain still over a time period, making this measure difficult to obtain in children. As a result, this study was undertaken to determine the effectiveness of using ECG R‐wave‐toe as an alternate method to measure PWV. Carotid‐toe PWV and R‐wave‐toe PWV were calculated for 31 healthy adolescents (16 females). Ten consecutive beats were averaged for each subject to determine the pulse transit time for each PWV method. PWV was calculated by dividing the pulse transit time by the distance travelled between the two recording sites for each method. A paired t‐test and Pearson correlation were conducted and significance was set at p<0.05. PWV estimated by the R‐wave‐toe technique was significantly lower than that estimated by the carotid‐toe technique (3.86 vs. 4.50 m/s, p<0.001). As well, a positive correlation was found between the two methods (r = 0.86, R 2 = 0.75, p<0.001). Although based on a small sample, these results suggest that R‐wave‐toe measurement technique may be a simple and useful alternate method to obtain PWV in children. Grant Funding Source : Supported by Canadian Institutes of Health Research