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Neuronal networks on the nano alumina templates (1127.4)
Author(s) -
Islam Asiful,
Me Latika
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1127.4
Subject(s) - template , nano , nanotechnology , materials science , nanoscopic scale , adhesion , biophysics , chemistry , biology , composite material
The hippocampus neuron cells were cultured on the nano‐alumina substrates. Several adhesion protein molecules e.g. Poly D Lysine (PDL), collagen (ECL) and leminin were applied as an interface in between the Al2O3 nano‐templates and the neuronal network before culturing the cells on top of them. The neuronal tissues were mechanically dissociated and cultured on the alumina nano template surfaces and incubated in an incubator. The cells grew on the top of the templates for 24 days. The well‐defined neuronal networks observed on the surface of the Al2O3‐nano templates. For control study, we also cultured neurons on the glass‐slip surfaces. This study revealed that the neurons can grow on any nano‐scale surfaces as well as on the standard cover slip if the proper growing environment will be provided.