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Effect of meal composition on postprandial blood glucose levels in middle aged and young adults (1107.6)
Author(s) -
Koch Carynn,
Koch Jennifer,
Hopper Mari
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1107.6
Subject(s) - postprandial , glycemic , waist , meal , medicine , endocrinology , glycemic load , circumference , glycemic index , insulin , obesity , geometry , mathematics
Effect of meal composition on postprandial blood glucose levels was determined in two cohorts, one middle aged (MA) (35‐55 years) and one young adult (YA) (19‐24 years). Subjects first completed an OGTT following an overnight fast. Over the next two weeks, and in random order, subjects consumed two breakfast meals varying in glycemic load: 1) high glycemic load (HGL); 2) low glycemic load (LGL). An Accucheck® glucometer determine fasted, 30, 60, and 120 minute postprandial blood glucose levels. Although fasted blood glucose levels were normal for all individuals, the mean value for the MA group was significantly higher than YA (87.1±0.70 vs. 82.9±0.67 mg/dl; p=0.0001). Mean blood glucose values following OGTT were normal and similar for the two groups. Following HGL and MGL meal consumption, blood glucose values for MA were higher than YA at 30 and 60 min and AUC’s were also significantly higher (13724±388 vs. 12780±354; p=0.042 and 12896±335 vs. 11703±212; p=0.003). The MA individuals with high waist circumference (WC>88cm) demonstrated significantly higher OGTT values than MA with normal waist circumference at 30 and 60 min (149.3±4.8 vs. 128.0±8.1; p=0.0273 and 147.2±7.6 vs. 118.6±11.6; p=0.0373). Following meal consumption high waist circumference individuals had higher blood glucose values than normal waist circumference at all time points with significant differences following MGL at 30 and 60 minutes. Grant Funding Source : Support received from the University of Southern Indiana Early Undergraduate Research Program