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Efficacy of a novel green coffee bean extract (GCB‐70) in weight management (1107.2)
Author(s) -
Swaroop Anand,
Bagchi Manashi,
Kumar Pawan,
Bagchi Debasis
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1107.2
Subject(s) - trigonelline , chlorogenic acid , caffeine , food science , vanillic acid , caffeic acid , antioxidant , chemistry , biochemistry , medicine , endocrinology
Green coffee beans (GCB) are the unroasted beans or raw seeds from the Coffee fruits, which are novel, natural source of a powerful antioxidant, chlorogenic acids, as well as caffeine, caffeic acid, vanillic acid, quinides, lignans and trigonelline. Chlorogenic acids enhance the taste and caffeine solubility. Chlorogenic acid has been demonstrated to reduce the absorption of fat from food intake and improves glucose metabolism, and promotes anti‐aging pathophysiology. Our laboratories have developed a novel, patented GCB extract GCB‐70 enriched with 70% total chlorogenic acids (tCGA) which includes 35% of 5‐caffeoylquinic acid (5‐CQA). The presently available GCB extracts contain only 45% tCGA including 15% 5‐CQA. Studies demonstrated that GCB‐70 is safe, potent, which potentiates antioxidant efficacy against oxidative stress, regulates blood pressure and improve cognitive functions. Furthermore, GCB‐70 accelerates glucose and fat metabolism, and may be an effective and inexpensive means for weight management. These results are very encouraging. Further research studies are in progress. Grant Funding Source : Company