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Effect of passive heating on arterial compliance in smokers vs. non‐smokers (1106.1)
Author(s) -
Moyen Nicole,
Ganio Matthew,
Burchfield Jenna,
Tucker Matthew,
Gonzalez Melina,
Dougherty Erin,
Robinson Forrest,
Ridings Christian,
Veilleux Jennifer
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1106.1
Subject(s) - medicine , pulse wave velocity , cardiology , compliance (psychology) , core temperature , endocrinology , blood pressure , psychology , social psychology
An inverse relationship exists between baseline arterial compliance (AC) and changes with passive heating in non‐smokers, yet it is unknown if this relationship exists in smokers. Purpose : To examine the effects of passive heating on AC in chronic smokers (S) vs. non‐smokers (NonS). Methods: 13 S and 13 NonS (27.2 ± 7.9 y; 78.8 ± 15.4 kg; 177.6 ± 6.7 cm) were passively heated until core temperature (T C ) increased 1.5 °C from baseline. At baseline and each 0.5 °C T C increase, AC was assessed peripherally and centrally using an ultrasound measuring pulse wave velocity (pPWV and cPWV, respectively). Results: Independent of group, cPWV significantly increased (p < 0.005) from baseline (grand mean: 526.7 ± 81.7 cm/s) to 1.5 °C (579.7 ± 69.8 cm/s). Regardless of group, pPWV did not change with heating (grand mean: baseline = 691.9 ± 92.9; 1.5 °C = 691.9 ± 79.5 cm/s; p > 0.05). Changes in cPWV and pPWV with heating negatively correlated (p < 0.05) with baseline PWV in S (cPWV: r = ‐0.59; pPWV: r = ‐0.62) and NonS (cPWV: r = ‐0.45; pPWV: r = ‐0.77). However, the magnitude of these relationships did not differ between S and NonS, either centrally or peripherally (p > 0.05). Conclusion : Passive heating to a 1.5 °C T C increase similarly affected AC in S and NonS. Inverse relationships between baseline PWV and changes in PWV with heating suggest the effect of heat on AC depends on baseline normothermic compliance. Grant Funding Source : Supported by: Arkansas Biosciences Institute, Arkansas Tobacco Settlement Proceeds Act of 2000