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Screening of some natural products and nanoparticles for their anti‐breast cancer activities (1048.13)
Author(s) -
Ahweyevu Charles,
Taha Murtada
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1048.13
Subject(s) - breast cancer , cancer , medicine , traditional medicine , disease , oncology , cancer research
Screening of some natural products and nanoparticles for their anti‐breast cancer activities Charles T. Ahweyevu 1 , Murtada A. Taha 2 , 1 Department of Natural Science, 2 Albany State Univeristy, Albany, Ga Cancer refers to a broad group of diseases that involve unregulated cell growth that form malignant tumors, which ultimately lead to death. Breast cancer is the most common type of cancer in women living in Western nations. It is estimated that approximately 1 in 8 North American females will develop breast cancer throughout their lifetime. The best way to battle cancer or any disease is prevention. One of the most researched aspects of chemoprevention is the use of natural products due to its cost effectiveness and little toxic side effects as opposed to other synthetic methods of chemo‐treatment. Herein, we employed both biochemical and microscopic techniques to investigate the anti‐breast cancer activities of seven different preparations namely; Milk thistle extract (MTE), Ginkgo biloba extract (GBE), Selenium (Se), Se‐MTE, Se‐GBE, chitosan, and Se‐chitosan nanoparticles. These natural products have previously shown to have various forms of anti‐cancer activities. Our results showed that only selenium and chitosan have promising anti‐breast cancer activities according to the MTT and microscopy results. Further studies are required to confirm this result.