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Serum 25‐hydroxy vitamin D is associated with blood total cholesterol and diastolic blood pressure in a young multi‐ethnic group living in South Florida (1041.15)
Author(s) -
Ajabshir Sahar,
Exebio Joel,
Zarini Gustavo,
Nayer Ali,
Vaccaro Joan,
Shaban Lemia,
Huffman Fatma
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1041.15
Subject(s) - blood pressure , medicine , vitamin d and neurology , diastole , body mass index , vitamin , cholesterol , endocrinology , physiology
Objective: The aim of this study was to investigate the relationship between serum 25‐hydroxy vitamin D, total cholesterol and blood pressure (BP) among young multi‐ethnic participants living in South Florida. Methods: This cross‐sectional study included 80 young adults, males (n=42) and females (n=38), ages 18‐36 years recruited from Florida International University campus. Serum 25‐hydroxy vitamin D and TC were measured by ELISA method. Systolic and diastolic BPs were measured by an automated monitor. Weekly total sun exposure and daily vitamin D intake were calculated from validated sun exposure and food frequency questionnaires respectively. A multi‐linear regression model was run, adjusting for age, gender, body mass index, systolic BP, daily vitamin D intake, total weekly sun exposure and tobacco use. Results: Total cholesterol (P= 0.020) and diastolic blood pressure (P= 0.025) were negatively associated with serum 25‐hydroxy vitamin D. This association remained significant after controlling for covariates (B= ‐0.074, P=.045 for total cholesterol, B= ‐0.421, P= ‐0.018 for diastolic blood pressure). The model explained 18.4% of the variation in serum 25‐hydroxy vitamin D. Conclusion: The results of this study suggest that high total blood cholesterol and diastolic blood pressure may be associated to low serum 25‐hydroxy vitamin D level. Interventions are needed to confirm these results. Grant Funding Source : Supported by NIH/NIDDK sponsored grant.