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Snacking influences adipokine concentration independent of body composition and inflammation in overweight humans (1039.2)
Author(s) -
Clayton Zachary,
Fusco Elizabeth,
Kass Lisa,
Carpenter Jennifer,
Hooshmand Shirin,
Hong Mee Young,
Kern Mark
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1039.2
Subject(s) - snacking , adipokine , adiponectin , leptin , overweight , endocrinology , medicine , adipose tissue , obesity , composition (language) , chemistry , food science , insulin resistance , linguistics , philosophy
Adipose tissue is a major energy reserve of the human body. It is also a source of the primary adpidocytokines leptin and adiponectin. The expression of adiponectin, specifically high‐molecular weight adiponectin (HMW‐A), and leptin have been demonstrated to decrease and increase, respectively, in relation to an increase in subcutaneous fat. Furthermore, HMW‐A and high sensitivity C‐reactive protein (hs‐CRP) have been demonstrated to have a reciprocal relationship. Effects of eight weeks of twice daily snacking (100 kcals each) of either a whole food (dried plums) or refined food (low‐fat muffins) on adipokines, body composition and hs‐CRP were assessed. HMW‐A decreased from baseline to eight weeks ( p < .05) during the muffin intervention, demonstrating a non‐significant, two‐fold greater decrease than during the dried plum trial. No difference was seen in body weight, body composition, leptin or hs‐CRP. This suggests that the addition of energy through snacking to usual dietary intake, regardless of nutrient composition, may not be advantageous in promoting anthropometric or metabolic alterations in overweight individuals. Grant Funding Source : Supported by the California Dried Plum Board