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Effect of dairy foods vs. calcium and vitamin‐D supplements on bone metabolism: use of 41Ca tracer (1018.12)
Author(s) -
Demmer Elieke,
Gertz Erik,
Rogers Tara,
Hillgonds Darren,
Garrod Marge,
Van Loan Marta
Publication year - 2014
Publication title -
the faseb journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.709
H-Index - 277
eISSN - 1530-6860
pISSN - 0892-6638
DOI - 10.1096/fasebj.28.1_supplement.1018.12
Subject(s) - calcium , vitamin d and neurology , bone remodeling , zoology , urine , medicine , chemistry , vitamin , dairy foods , bone resorption , food science , endocrinology , biology
Effect of dairy foods vs calcium & vitamin‐D supplements on bone metabolism: Use of 41Ca tracer E Demmer 1 , ER Gertz 2 , T Rogers 1 , D Hillgonds 3 , M Garrod 2 , MD Van Loan 2 1. Graduate Group in Nutritional Biology, University of California Davis, Davis, CA 2. USDA/ARS Western Human Nutrition Research Center, Davis, CA 3. Lawrence Livermore National Laboratory, Livermore, CA Calcium(Ca) & vitamin D (D) are essential for bone health but other dietary components may also be important. Dairy products provide a rich supply of Mg, P, K, and protein, all important to bone health. We examined the effect of 4 servings/d milk & yogurt compared to equal intakes of Ca & D from supplements on bone metabolism. Twelve healthy postmenopausal women, who were low‐moderate dairy consumers, completed a randomized crossover trial with two 6 wk interventions separated by a 6 wk washout period. Six months prior to intervention women were dosed with 41Ca to label the skeleton. 24‐hr urine samples were analyzed for 41Ca/40Ca using accelerator mass spectrometry. Both interventions resulted in a significant decline (p < 0.0001) of Ca lost from the skeleton. Reduced resorption for supplement (p=0.0034) and dairy (p= 0.0002) groups was confirmed by CTx. Formation (BAP) significantly increased (p=0.032) in the dairy group only. Ca intake for the dairy group was significantly less (‐120mg/d) than that consumed by supplements, this difference can be attributed to other dietary Ca sources, e.g. increased vegetable and grain intake in the supplement group. Our results suggest that the nutrient‐rich composition of milk and yogurt may be more effective in maintaining bone health in healthy postmenopausal women compared to Ca and D supplements alone. Funding: Dairy Research Institute, California Dairy Council, USDA‐ARS‐Western Human Nutrition Research Center Grant Funding Source : Dairy Research Institute, California Dairy Council, USDA‐ARS‐Western Human Nutrition Research Center